Search Results

1 of 1
Edit My Search | New Search | Selected Items
thumbnail image
PDF
PDF-1(2.08 MB)
Citation & Export
View statistics
Staff View

Citation & Export
Hide

Simple citation

Huang, Lei & Guo, Zhixiong (2012). Nanofiltration and sensing of picomolar chemical residues in aqueous solution using an optical porous resonator in a microelectrofluidic channel. Nanotechnology, 23(6), 065502-. Retrieved from https://doi.org/doi:10.7282/T30R9RP5

Export

Click here for information about Citation Management Tools at Rutgers.

Statistics
Hide

Description

Nanofiltration and sensing of picomolar chemical residues in aqueous solution using an optical porous resonator in a microelectrofluidic channel (2012)
Lei Huang, Zhixiong Guo
Nanotechnology 23(6): 065502-.
Link to published version
VersionAccepted Manuscript (AM)
AbstractFor the first time the use a porous microresonator placed in a microelectrofluidic system for integrated functions of nano filtration and sensing of small biomolecules and chemical analytes in extremely dilute solution was proposed and investigated. As an example, aminoglycosides in drug residues in food and livestock products were considered as the trace chemical analyte. The filtration process of the charged analyte in aqueous solution driven by an applied electrical field and the accompanied optical whispering-gallery modes in the resonator are modeled. The dynamic process of adsorption and desorption of the analyte onto the porous matrix is studied. The analyte deposition inside the porous structure will alter the material refractive index of the resonator, and thus, induce optical resonance frequency shift. By measuring the optical frequency shift, the analyte concentration as well as the absorption/desorption process can be analyzed. Through an intensive numerical study, a correlation between the frequency shift and the analyte concentration and the applied electrical voltage gradient was obtained. It reveals a linear relationship between the resonance frequency shift and the analyte concentration. The applied electrical voltage enhances substantially the filtration capability and the magnitude of the optical frequency shift, pushing the porous resonator-based sensor to function at the extremely dilute picomolar concentration level for small bio/chemical molecules down to the sub-nanometer scale. Moreover, use of the second-order whispering-gallery mode is found to provide better sensitivity as compared with the first-order mode.
Persistent URLhttps://doi.org/doi:10.7282/T30R9RP5
SubjectsChemical residues, Nanoscale sensing, Molecular sensing, Optical sensor, Microelectrofluidics, Molecules
RightsCopyright for scholarly resources published in RUcore is retained by the copyright holder. By virtue of its appearance in this open access medium, you are free to use this resource, with proper attribution, in educational and other non-commercial settings. Other uses, such as reproduction or republication, may require the permission of the copyright holder.