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Bhise, Vikram & Buyukturkoglu, Korhan & Matilde , Inglese & Wollack, Jan & Balashov, Konstantin (2015). Severe progressive brain atrophy in pediatric multiple sclerosis. Journal of Pediatric Neurology, 4(2), 32-35. Retrieved from https://doi.org/doi:10.7282/T3028TS2

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Severe progressive brain atrophy in pediatric multiple sclerosis (2015)
Vikram Bhise, Korhan Buyukturkoglu, Inglese Matilde, Jan Wollack, Konstantin Balashov
Journal of Pediatric Neurology 4(2): 32-35.
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AbstractBACKGROUND: Multiple sclerosis is an immune-mediated disease of the central nervous system. Progressive brain atrophy is a known marker of patient disability and cognitive impairment in MS patient, but limited information is available about the clinical and cognitive consequences in the pediatric population. CASE REPORT: We present a case of aggressive pediatric-onset MS with severe rapidly progressive brain atrophy, neurological disability, and cognitive deterioration. Serial brain MRI studies demonstrate ongoing cerebral atrophy correlating with severe deficits on serial neuropsychological testing. CONCLUSIONS: A subset of pediatric MS patient may be vulnerable to severe cognitive deterioration associated with marked brain atrophy.
Persistent URLhttps://doi.org/doi:10.7282/T3028TS2
SubjectsMultiple sclerosis, Magnetic resonance imaging, Neuropsychology, Childhood
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